Irini Konstantinidi was born in Athens and started studying classical piano at the age of 5. She studied at the Music High School of Pallini, also at the Department of Primary Education at Athens University and at the Athenaeum Conservatory.

She completed her master in Jazz Vocals at the Royal Conservatoire of The Hague in 2018.

She has performed in many venues and festivals in Greece and the Netherlands and has collaborated with the Athens Big Band, the Metropole Orchestra Academy of the Netherlands, as well as with many leading Greek and Dutch musicians.

Along with the drummer Thanos Hatzianagnostou she founded The Wonderfall Quartet, releasing their debut album in 2012. She also founded the Jazz-bound Project. She is also a member of the Nomadic Treasures project, which released its first album in 2018.

Her debut personal album "Nothing to Lose" was released in 2021.

She teaches jazz vocals and improvisation.