Dimitris Karaganis was born in Piraeus. He studied classical flute at the Hellenic Conservatory with Spiros Papikinos and at the Athens Conservatory with Swiss flutist Urs Ruttiman. From very early, his interest for the improvisation and jazz leads him to study the saxophone and piano. In addition to his studies on classical music, he was engaged in Jazz and has cooperated with many acclaimed Jazz musicians of the Greek Jazz Scene.

Among others he has collaborated with Andreas Georgiou, Danny Hayes, Aroma Caribe and has performed with various groups in Athens and in Thessaloniki.

He was a founding member of the Empnus Jazz Quintet.